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Synthetic Approaches to the 2008 New Drugs

[ Vol. 9 , Issue. 14 ]


Kevin K.-C. Liu, Subas M. Sakya, Christopher J. O'Donnell and Jin Li   Pages 1655 - 1675 ( 21 )


New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 18 NCEs marketed in 2008.


Synthesis, New Drug, New Chemical Entities, Medicine, Therapeutic Agents


Pfizer Inc, La Jolla, CA 92037, USA.

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