Bettina Jungwirth, Walter Zieglgansberger, Eberhard Kochs and Gerhard Rammes Pages 1568 - 1579 ( 12 )
POCD describes a decline in cognitive function after surgery with a predominance in the elderly patient. Although there is general agreement that POCD is likely to be multifactorial, it remains unclear whether its occurrence is a result of the effects of surgery or general anesthesia. This review provides a synopsis of the available clinical and preclinical data and summarizes recent research relevant to the occurrence of POCD and possible pharmacologic algorithms for its prevention and treatment., Anesthesia, and, Postoperative, Cognitive, Dysfunction, (POCD)
Department of Anesthesiology,Technische Universitat Munchen, Klinikum Rechts Der Isar, Munich,Germany.