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New Potential Targets to Modulate Neutrophil Function in Inflammation

[ Vol. 9 , Issue. 2 ]

Author(s):

R. A. Burgos, M. A. Hidalgo, C. D. Figueroa, I. Conejeros and J. L. Hancke   Pages 153 - 168 ( 16 )

Abstract:


The importance of neutrophils in human disease such as rheumatoid arthritis, asthma, adult respiratory distress syndrome, and COPD has prompted the search for drugs capable to slow down neutrophil-dependent inflammation, without interference with innate immune responses. In this review, we summarize new potential drugs targets against neutrophils mediated inflammatory responses.

Keywords:

Neutrophil, drugs, innate immunity, inflammation

Affiliation:

Laboratory of Molecular Pharmacology, Institute of Pharmacology, Faculty of Veterinary Sciences, Universidad Austral de Chile, Casilla 567, Valdivia, Chile.



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