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Chemistry and Pharmacology of Collinin, Active Principle of Zanthoxylum spp.

[ Vol. 8 , Issue. 12 ]


Francesco Epifano, Salvatore Genovese, Maria Carla Marcotullio and Massimo Curini   Pages 1203 - 1208 ( 6 )


Collinin is a geranyloxycoumarins isolated in small amounts from plants of the Rutaceae family. Synthetic schemes were recently developed allowing to handle collinin in sufficient quantities to put in evidence valuable biological effects. The aim of this review is to examine the phytochemical and pharmacological properties of this compound.


Anti-inflammatory activity, anti-cancer activity, collinin, geranyloxycoumarins, rutaceae


Dipartimento di Scienze del Farmaco, Universita “G. D'Annunzio”, Via dei Vestini 31, 66013 Chieti Scalo (CH), Italy.

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