R. Fringuelli, L. Milanese and F. Schiaffella Pages 1061 - 1073 ( 13 )
1,4-Benzothiazine (1,4-BT) derivatives have been reported to exhibit a wide range of pharmacological properties including antifungal, immunostimulating, anti-aldoso-reductase, anti-rheumatic, anti-allergic, vasorelaxant, anti-arrhythmic, anti-hypertensive, neuroprotective and cytotoxic activities. These different effects indicate that 1,4-BT is a template potentially useful in medicinal chemistry research and therapeutic applications.
Candida infections, Rheumatoid arthritis, ALDOSE-REDUCTASE INHIBITORS, benzothiazepine nucleus, nimodipine, NEUROPROTECTIVE, anti-tumor
Department of Drug Chemistry and Technology, Via del Liceo, University of Perugia, 06123 Perugia, Italy.