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Natural Products as Angiogenesis Modulators

[ Vol. 5 , Issue. 11 ]


K. A. El Sayed   Pages 971 - 993 ( 23 )


Cancer remains one of the major causes of death worldwide. Anti-angiogenic therapy is one of the new approaches to anticancer therapy. Out of 22 angiogenesis inhibitors currently under clinical trials there are 11 natural products or were modeled on a natural product parent. This review shows the potential of natural products for the discovery of new anti-angiogenic leads.


cancer, angiogenesis modulators, plant, marine, microbial natural products


Department of Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monore, Monore, LA 71209, USA.

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