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Article Details


Molecular Targets of FoxP3+ Regulatory T Cells

[ Vol. 7 , Issue. 11 ]

Author(s):

Chang H. Kim   Pages 1136 - 1143 ( 8 )

Abstract:


The important roles of FoxP3+ T cells in many immunological or cancerous diseases are now well established. The research field is now moving in the direction to fine-control the generation, migration, expansion, and function of FoxP3+ cells in an effort to prevent and cure specific types of diseases. Potential molecular targets to regulate FoxP3+ T cells are reviewed in this article.

Keywords:

FoxP3, regulatory T cells, tolerance, diseases, migration, chemokine receptors

Affiliation:

Department of Comparative Pathobiology, 725 Harrison Street, Purdue University, West Lafayette, IN 47907, USA.



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