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Aptamer-Based Strategies for Stem Cell Research

[ Vol. 7 , Issue. 7 ]

Author(s):

Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer, Hans P. Wendel, Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer and Hans P. Wendel   Pages 701 - 705 ( 5 )

Abstract:


Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.

Keywords:

Mesenchymal stem cells, aptamer, FACS analysis

Affiliation:

University Hospital Tuebingen,Dept. of Thoracic, Cardiac, and Vascular Surgery, Clinical Research Laboratory,Calwerstr.7/1, 72076 Tuebingen, Germany., University Hospital Tuebingen,Dept. of Thoracic, Cardiac, and Vascular Surgery, Clinical Research Laboratory,Calwerstr.7/1, 72076 Tuebingen, Germany.



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