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Synthetic Approaches to the 2005 New Drugs

[ Vol. 7 , Issue. 4 ]

Author(s):

Subas M. Sakya, Jin Li and Kevin K.-C. Liu   Pages 429 - 450 ( 22 )

Abstract:


New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 22 NCEs marketed in 2005.

Keywords:

Synthesis, new drug, new chemical entities, medicine, therapeutic agents

Affiliation:

Pfizer Global Research and Development, Pfizer Inc., Groton, CT 06340, USA.



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