Jesus Alcazar, Gaston Diels and Bruno Schoentjes Pages 345 - 369 ( 25 )
Microwave irradiation has been used to enhance organic reactions since the mid 80s, its use within the field of medicinal chemistry is not so widely evident in the literature. The present review highlights the use of microwave chemistry as an important tool for the fast development of structure activity relationship in several programs related to various therapeutic areas.
Microwave, medicinal chemistry, SAR development
Johnson&Johnson Pharmaceutical Research and Development, Division of Janssen-Cilag, S.A. Jarama s/n. 45007 Toledo, Spain.