D. J. Miller and R. K. Allemann Pages 107 - 113 ( 7 )
myo-Inositol monophosphatase has long been a target for drug discovery. Recent work has given detailed insight into its mechanism and dynamics plus new activities and some novel series of inhibitors. The goal of a bio-available inhibitor for this enzyme, however, remains a major challenge for medicinal chemistry.
diacylglycerol, G-protein coupled receptor, Lithitum, myo-Inositol 1-phosphate, Circular dichroism, Zinc ion
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