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Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat

[ Vol. 7 , Issue. 1 ]


J.-P. Chaput, S. St-Pierre and A. Tremblay   Pages 3 - 10 ( 8 )


The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.


Pharmacotherapy, sibutramine, orlistat, body weight, fat, energy balance, physical activity, diet


Division of Kinesiology (PEPS), Laval University, Sainte-Foy, Qu├ębec, Canada, G1K 7P4.

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