Submit Manuscript  

Article Details

Carbohydrate-Based Scaffolds in Drug Discovery

[ Vol. 6 , Issue. 12 ]


Bernd Becker, Glenn C. Condie, Giang Thanh Le and Wim Meutermans   Pages 1299 - 1309 ( 11 )


Carbohydrates have been proven as valuable scaffolds to display pharmocophores and the resulting molecules have demonstrated useful biological activity towards various targets including the somatostatin receptors (SSTR), integrins, HIV-1 protease, matrix metalloproteinases (MMP), multidrug resistance-associated protein (MRP), and as RNA binders. Carbohydrate-based compounds have also shown antibacterial and herbicidal activity.


Carbohydrates, combinatorial chemistry, carbohydrate scaffolds, mimetics


Alchemia Ltd, PO Box 6242, Upper Mt Gravatt, Qld 4122, Australia.

Read Full-Text article