Bernd Becker, Glenn C. Condie, Giang Thanh Le and Wim Meutermans Pages 1299 - 1309 ( 11 )
Carbohydrates have been proven as valuable scaffolds to display pharmocophores and the resulting molecules have demonstrated useful biological activity towards various targets including the somatostatin receptors (SSTR), integrins, HIV-1 protease, matrix metalloproteinases (MMP), multidrug resistance-associated protein (MRP), and as RNA binders. Carbohydrate-based compounds have also shown antibacterial and herbicidal activity.
Carbohydrates, combinatorial chemistry, carbohydrate scaffolds, mimetics
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