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Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs

[ Vol. 6 , Issue. 7 ]

Author(s):

Ryan Craig and Shulin Li   Pages 757 - 764 ( 8 )

Abstract:


Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits ofreducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review willdiscuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.

Keywords:

Peptide, tumor-targeting, tumor vessel, gene therapy, gene delivery, drug delivery, adhesion molecule, phage display

Affiliation:

Department of ComparativeBiomedical Sciences, Louisiana State University, Skip Bertman Drive,Baton Rouge, LA 70803, USA.



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