Seoung J. Park and Yong C. Lee Pages 235 - 240 ( 6 )
Oxidative stress plays an important role in the pathogenesis of asthma. Recently several investigators have studied the effects of a variety of antioxidants on asthma. Antioxidants, including L-2- oxothiazolidine-4-carboxylic acid, reduce airway inflammation and hyper-responsiveness of asthma and may be novel therapeutic agents for asthma.
Asthma, L-2-oxothiazolidine-4-carboxylic acid, N-acetyl-L-cysteine, NF-?B, oxidative stress, reactive oxygen species, antioxidant
Department of InternalMedicine, Chonbuk National University Medical School, 634-18,Keumamdong, Jeonju, 561-712, South Korea.