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Development of Miltefosine for the Leishmaniases

[ Vol. 6 , Issue. 2 ]


J. D. Berman   Pages 145 - 151 ( 7 )


The leishmaniases consist of visceral and cutaneous syndromes present in > 30 endemic regions of the world. Miltefosine (hexadecylephosphocholine) is the first oral agent that is effective and tolerated for both visceral and cutaneous disease in several endemic regions, and represents a major advance in the treatment of these diseases.


Miltefosine, visceral leishmaniasis, cutaneous leishmaniasis, efficacy, tolerance


National Center ForComplementary and Alternative Medicine, National Institutes of Health,6707 Democracy Blvd, Suite 401, Bethesda MD 20892 USA.

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