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Development of Miltefosine for the Leishmaniases

[ Vol. 6 , Issue. 2 ]

Author(s):

J. D. Berman   Pages 145 - 151 ( 7 )

Abstract:


The leishmaniases consist of visceral and cutaneous syndromes present in > 30 endemic regions of the world. Miltefosine (hexadecylephosphocholine) is the first oral agent that is effective and tolerated for both visceral and cutaneous disease in several endemic regions, and represents a major advance in the treatment of these diseases.

Keywords:

Miltefosine, visceral leishmaniasis, cutaneous leishmaniasis, efficacy, tolerance

Affiliation:

National Center ForComplementary and Alternative Medicine, National Institutes of Health,6707 Democracy Blvd, Suite 401, Bethesda MD 20892 USA.



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