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Recent Advances in Combinatorial Chemistry Applied to Development of Anti-HIV Drugs

[ Vol. 6 , Issue. 1 ]

Author(s):

S. Pettersson, I. Clotet-Codina, J. A. Este, J. I. Borrell and J. Teixido   Pages 91 - 108 ( 18 )

Abstract:


A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.

Keywords:

Combinatorial chemistry, synthesis, anti-HIV drugs, high throughput screening

Affiliation:

Grup d'Enginyeria Molecular (GEM), Institut Quimic de Sarria (IQS), Universitat Ramon Llull, Via Augusta 390, E-08017 Barcelona, Spain



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