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Research Development, Optimization and Modifications of Anti-cancer Peptides

[ Vol. 21 , Issue. 1 ]

Author(s):

Zhi-Gang Sun*, Liang-Hui Zhao, Stacy Mary Yeh, Zhi-Na Li and Xin Ming*   Pages 58 - 68 ( 11 )

Abstract:


Anti-cancer peptides play an important role in the area of cancer inhibition. A variety of anti- cancer peptides have emerged through the extraction and structural modification of peptides from biological tissues. This review provides the research background of anti-cancer peptides, the introduction of the mechanism of anti-cancer peptides for inhibition of cancers, the discovery and development along with optimization and modifications of these peptides in the clinical application. In conclusion, it can be said that anti-cancer peptides will play a major role in the future oncologic clinic.

Keywords:

Anti-cancer peptides, modifications, mechanisms, progress, development, optimization.

Affiliation:

Central Laboratory, Linyi Central Hospital, No. 17 Jiankang Road, Linyi 276400, Weifang Medical University, No. 7166 Baotong West Street, Weifang 261000, Departments of Cancer Biology and Biomedical Engineering, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston- Salem, NC 27101, Central Laboratory, Linyi Central Hospital, No. 17 Jiankang Road, Linyi 276400, Departments of Cancer Biology and Biomedical Engineering, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston- Salem, NC 27101



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