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Research Development, Optimization and Modifications of Anti-cancer Peptides

Author(s):

Zhi-Gang Sun*, Liang-Hui Zhao, Stacy Mary Yeh, Zhi-Na Li and Xin Ming   Pages 1 - 11 ( 11 )

Abstract:


Anti-cancer peptides play an important role in the area of cancer inhibition. A variety of anti-cancer peptides have emerged through the extraction and structural modification of peptides from biological tissues. This review provides the research background of anti-cancer peptides, the introduction on the mechanism of anti-cancer peptides in inhibition of cancers, the discovery and development of anti-cancer peptides, and the optimization modifications of anti-cancer peptides in the clinical application. In conclusion, anti-cancer peptides will play a greater role in the future oncologic clinic.

Keywords:

Anti-cancer peptides, Modifications, Mechanisms, Progress, Development, Optimization

Affiliation:

Central Laboratory, Linyi Central Hospital, No.17 Jiankang Road, Linyi 276400, Weifang Medical University, No.7166 Baotong West Street, Weifang 261000, Departments of Cancer Biology and Biomedical Engineering, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, Central Laboratory, Linyi Central Hospital, No.17 Jiankang Road, Linyi 276400, Departments of Cancer Biology and Biomedical Engineering, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157



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