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The Chemistry of Triazine Isomers: Structures, Reactions, Synthesis and Applications


Neelottama Kushwaha* and C S Sharma   Pages 1 - 19 ( 19 )


Triazine is the six-membered heterocyclic ring containing three nitrogen which replaces carbon-hydrogen unit in the benzene ring. Based on nitrogen position present in the ring system, it is categorized in three isomeric forms i.e.1, 2, 3-triazine (vicinal triazine), 1, 2, 4-triazine (asymmetrical triazine or isotriazine) and 1, 3, 5-triazine (symmetrical or s-triazine or cyanidine). Triazines have weakly basic property. Its isomers have much weaker resonance energy than benzene structure, so nucleophilic substitution reactions are more preferred than electrophilic substitution reactions. Triazine isomers and their derivatives are known to play important roles possessing various activities in medicinal and agricultural fields such as anti-cancer, antiviral, fungicidal, insecticidal, bactericidal, herbicidal, antimalarial and antimicrobial agents.


Heterocyclic, triazines, chemical reactivity, triazine synthesis, potent, biological activity.


Department of Pharmacy, Pranveer Singh Institute of Technology, Kanpur-209305, Bhupal Nobles University, Udaipur, Rajasthan-313001

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