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Pharmacological analysis of Cannabis sativa: A potent herbal plant

Author(s):

Muhammad Husnain, Muhammad Imran*, Muhammad Ibrahim, Mohammad Ali Assiri, Naveed Zubair Wattoo and Ahmad Irfan   Pages 1 - 31 ( 31 )

Abstract:


Genus Cannabis belong to family Cannabaceae and is traditionally used as medicinal plant against many diseases notably asthma, malaria, treatment of skin diseases, diabetes and headache. The plant Cannabis sativa L. is flowering and an annual herbaceous plant located to eastern Asia but now of cosmopolitan distribution due to extensive cultivation.

Aim of the study: The aim of review is to provide a complete evaluation of the botanical, ethnological and chemical aspects of Cannabis sativa L., and its importance in pharmacological studies.

Results and discussions: This article briefly reviews the botany, traditional knowledge, pharmacological and therapeutic application of the plant C. sativa. This is an attempt to compile and document information about the chemical constituent, pharmacological and therapeutic effects of C. sativa as important herbal drug due to its safety and effectiveness. Studies have revealed its use as anti-bacterial, anti-fungal, anti-cancer, anti-inflammatory and improving testicular function in rats. Consumption of C. sativa is greater in all over the world among all other drugs of abuse in its various forms such as marijuana, hashish and cannabis oil. The study of herbal medicine spans the knowledge of biology, history, source, physical and chemical nature, and mechanism of action, traditional, medicinal and therapeutic use of drug. This article also provide knowledge about macroscopically and microscopically characters of Cannabis sativa with geographical sources. The wellknown cannabinoids are Tetrahydrocannabinol (THC), Cannabidiol (CBD) and Cannabichromene (CBC) and their pharmacological properties and importance have been extensively studied. Hence, efforts are required to establish and validate evidence regarding safety and practices of Ayurveda medicines.

Conclusion: Thes studies will help in expanding the current therapeutic potential of C. sativa and it also provide a strong support to its future clinical use as herbal medicines having safe in use with no side effects.

Keywords:

Cannabaceae, Cannabis sativa L., phytochemical constituents, ethnopharmacological aspects, clinical trial.

Affiliation:

Department of Applied Chemistry, Government College University Faisalabad, Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Department of Applied Chemistry, Government College University Faisalabad, Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Department of Applied Chemistry, Government College University Faisalabad, Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413



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