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Antimicrobial Effects of Chemical Compounds Isolated from Traditional Chinese Herbal Medicine (TCHM) Against Drug-Resistant Bacteria: A Review Paper

[ Vol. 19 , Issue. 2 ]

Author(s):

Yanling Zhao*, Haotian Li, Shizhang Wei, Xuelin Zhou and Xiaohe Xiao   Pages 125 - 137 ( 13 )

Abstract:


Infectious diseases caused by pathogenic bacteria seriously threaten human lives. Although antibiotic therapy is effective in the treatment of bacterial infections, the overuse of antibiotics has led to an increased risk of antibiotic resistance, putting forward urgent requirements for novel antibacterial drugs. Traditional Chinese herbal medicine (TCHM) and its constituents are considered to be potential sources of new antimicrobial agents. Currently, a series of chemical compounds purified from TCHM have been reported to fight against infections by drug-resistant bacteria. In this review, we summarized the recent findings on TCHM-derived compounds treating drug-resistant bacterial infections. Further studies are still needed for the discovery of potential antibacterial components from TCHM.

Keywords:

Traditional Chinese Herbal Medicine (TCHM), drug-resistant bacteria, TCHM-derived compounds, antibacterial effect, shigellosis, tuberculosis.

Affiliation:

Department of Pharmacy, 302 Military Hospital of China, Beijing, 100039, Department of Pharmacy, 302 Military Hospital of China, Beijing, 100039, Department of Pharmacy, 302 Military Hospital of China, Beijing, 100039, Department of Pharmacy, 302 Military Hospital of China, Beijing, 100039, China Military Institute of Chinese Medicine, 302 Military Hospital of China, Beijing, 100039

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