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Benzimidazole Derivatives as Potential Antimicrobial and Antiulcer Agents: A Mini Review

[ Vol. 19 , Issue. 16 ]

Author(s):

Ali Mohd Ganie, Ayaz Mahmood Dar, Fairooz Ahmad Khan and Bashir Ahmad Dar*   Pages 1292 - 1297 ( 6 )

Abstract:


Here in we report the number of strategies for the synthesis of differently substituted benzimidazole derivatives. The protocols involved in the syntheses of these derivatives were one-pot or multi-component. The characterization studies of these derivatives were carried by using different spectroscopic techniques (1H NMR, 13C NMR and MS) and elemental analyses. The biological screening studies revealed that these benzimidazole derivatives show potential antibacterial as well as antifungal behavior. These benzimidazole derivatives not only depicted potential antiulcer properties but also showed moderate to good anticancer/cytotoxic behavior against different cancer cell lines.

Keywords:

Benzimidazoles, Antimicrobial, Antiulcer, Anticancer, Escherichia coli, Pseudomonas aeruginosa.

Affiliation:

Department of Chemistry, Bundelkhand University Jhansi U.P, Department of Chemistry, Govt. Degree College Kulgam 192231 J&K, Department of Chemistry, Govt. Degree College (Boys) Sopore 193201, Department of Chemistry, Govt. Degree College (Boys) Sopore 193201



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