Submit Manuscript  

Article Details


The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review

[ Vol. 18 , Issue. 11 ]

Author(s):

Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh   Pages 918 - 947 ( 30 )

Abstract:


Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry. This review presents a detailed overview on the synthesis, QSAR and pharmacological applications of pyrazole. In addition, it covers most recent reports on structural modifications on pyrazole illustrating vital structural activity relationship.

Keywords:

Combinatorial chemistry, medicinal chemistry, pharmacological activity, pharmacophore, pyrazole, QSAR.

Affiliation:

Department of Chemistry, Banasthali University, Banasthali Bansthali-304022, Department of Pharmacy, Banasthali University, Banasthali, Banasthali-304022, Department of Chemistry, Banasthali University, Banasthali Bansthali-304022, Department of Chemistry, Banasthali University, Banasthali Bansthali-304022

Graphical Abstract:



Read Full-Text article