A.S.G. Prasad, T. Bhaskara Rao, D. Rambabu, Mandava V. Basaveswara Rao* and Manojit Pal* Pages 895 - 903 ( 9 )
Background: SnCl2·2H2O has been used as a convenient precatalyst for the one-pot and rapid synthesis of 2-substituted quinolines under ultrasound irradiation in water. The reaction involved a 3-component reaction of aniline, aldehydes, and ethyl 3,3-diethoxypropionate in the presence of aerial oxygen to give the desired products in good yields.
Conclusion: Several of these compounds showed antibacterial activities when tested against gram-positive and gram-negative species. One compound i.e. 4b showed promising activities across both the species.
Antibacterial, MCRs, quinoline, ultrasound, water, SnCl2.
Department of Chemistry, K.L. University, Vaddeswaram Guntur-522502, Andhra Pradesh, Department of Chemistry, K.L. University, Vaddeswaram Guntur-522502, Andhra Pradesh, Department of Chemistry and The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Be'er-Sheva 84105, Department of Chemistry, Krishna University, Machilipatnam-521001, Andhra Pradesh, Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad 500046