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Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound

[ Vol. 17 , Issue. 1 ]


Shaoping Wu, Yaoyao Ning, Yingyong Zhao, Wenji Sun, Serge Thorimbert, Luc Dechoux, Matthieu Sollogoub and Yongmin Zhang   Pages 62 - 77 ( 16 )


Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.


Biological activity, biotransformation, gentiopicroside, natural product, secoiridoid, total synthesis.


Sorbonne Universit├ęs, UPMC Univ Paris 06, CNRS UMR 8232, 4 place Jussieu, 75005 Paris, France.

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