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Development of Arene Ruthenium Antitumor Complexes

[ Vol. 16 , Issue. 10 ]

Author(s):

Wei Su, Zhaofeng Tang and Peiyuan Li   Pages 787 - 795 ( 9 )

Abstract:


The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.

Keywords:

Anticancer agent, Arene, Biologically active ligands, Ruthenium.

Affiliation:

College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, China.



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