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A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

[ Vol. 16 , Issue. 2 ]

Author(s):

Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yaming Zhang, Ye Wang, Honghong Liu, Honghui Shen and Xiaohe Xiao   Pages 163 - 175 ( 13 )

Abstract:


Chinese herbal medicine (CHM), an alternative and complementary medicine, has been applied in various diseases. Recently, a number of anti-liver fibrogenesis compounds exhibiting antiliver fibrosis effects have been discovered in CHM. In this review, we reviewed the published data on their anti-fibrosis effects and discussed the possible underlying mechanisms. More investigations are needed to improve the insight into therapeutic effect of CHM on liver fibrosis.

Keywords:

Chinese herbal medicine, Extracellular matrix, Hepatic stellate cell, Liver fibrosis.

Affiliation:

China Military Institute of Chinese Medicine, 302 Military Hospital of China, Beijing, 100039, China.



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