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[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

[ Vol. 14 , Issue. 4 ]

Author(s):

Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui   Pages 355 - 369 ( 15 )

Abstract:


In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.

Keywords:

Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.

Affiliation:

Post Graduate and Research centre, Maulana Azad College, Aurangabad, and Indian Institute of Integrative Medicine Jammu 180001.



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