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Quinoline – a Promising Fragment in the Search for New Antimalarials

[ Vol. 14 , Issue. 4 ]

Author(s):

Beata Gryzło and Katarzyna Kulig   Pages 332 - 344 ( 13 )

Abstract:


Malaria continues to be a potentially fatal threat to almost half of the world's population. In the present review, efforts have been made to provide a literature concerning the study of quinoline as a privilege structure for search of new malarials. The review covers advances in that field made in few last years.

Keywords:

Antimalarials, antimicrobial activity, drug design, hybrid molecules, malaria, plasmodium falciparum, quinoline.

Affiliation:

Department of Physicochemical Drug Analysis, Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.



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