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Self-Assembled Potential Bio Nanocarriers for Drug Delivery

[ Vol. 13 , Issue. 9 ]

Author(s):

Nasima Akter, Shahidan Radiman, Faizal Mohamed and Mohammad Imam Hasan Reza   Pages 1327 - 1339 ( 13 )

Abstract:


Self-assembled nanocarriers attract increasing attention due to their wide application in various practical fields; among them, one of the most focused fields is drug delivery. Appropriate selection of surfactant is the basis for preparing a successful nanocarrier. Until now, from phospholipid to synthetic surfactants, many surfactants have been used to explore a suitable drug delivery vehicle for the complex in-vivo environment. Among all, bio surfactants are found to be more suitable due to their bio-origin, less-toxicity, biodegradability, cheaper rate and above all, their versatile molecular structures. This molecular property enables them to self assemble into fascinating structures. Moreover, binding DNA, enhancing pH sensitivity and stability allows novelty over their synthetic counterparts and phospholipid. This review paper focuses on the properties and applications of bio-nano-carriers for drug delivery. Micelle, microemulsion, and vesicle are the three nanocarriers which are discussed herein.

Keywords:

Biocompatible nanocarriers, biosurfactants, micelle, microemulsion, vesicle.

Affiliation:

School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM, Bangi, Selangor, Malaysia.



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