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Recent Updates on Biological Activities of Oxadiazoles

[ Vol. 13 , Issue. 7 ]

Author(s):

Rikta Saha, Omprakash Tanwar, Akranth Marella, M. Mumtaz Alam and Mymoona Akhter   Pages 1027 - 1046 ( 20 )

Abstract:


Among the plethora of heterocyclic nucleus discovered, the oxadiazoles have also been explored extensively. The oxadiazole structure has been demonstrated to bear important biological activities such as anti-cancer, antiinflammatory, anti-tuberculosis, anti-malarial and anti-schistosomiasis etc. The presence of oxadiazole motifs in diverse types of compounds proves its importance in the field of medicinal chemistry. This review is complementary to earlier reviews and covers recent updates of various pharmacological aspects of oxadiazoles. To help the reader better know the context for these approaches, a summary of various aspects of background of related topic is presented.

Keywords:

Biological activities, Five membered heterocyclic ring, Oxadiazole.

Affiliation:

Drug Design and Medicinal Chemistry Laboratory, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062, India.



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