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Bioactive Natural Products from the Antarctic and Arctic Organisms

[ Vol. 13 , Issue. 4 ]

Author(s):

Jing-Tang Liu, Xiao-Ling Lu, Xiao-Yu Liu, Yun Gao, Bo Hu, Bing-Hua Jiao and Heng Zheng   Pages 617 - 626 ( 10 )

Abstract:


Polar regions are remote and challenging areas on the earth. In view of the unique environment and the severe competition in polar regions, it’s considered that the ecological system might be the producer of new compounds with diversity biological activities. This review is an attempt to consolidate the studies about 97 natural products isolated from Antarctic and Arctic organisms including microbes, algae, sponges, bryozoans, and tunicates and so on published in the recent years. The emphasis is mainly about the new compounds, source organisms and biological activities, which signifies the immense competence of Antarctic and Arctic organisms as bioactive natural products producers.

Keywords:

Antibacterium, bioactivity, cytotoxicity, natural products, polar organisms, secondary metabolites, marine life, Candida albicans

Affiliation:

Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, No. 800, Xiangyin Rd., Shanghai 200433, People’s Republic of China.



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